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Forget "eye of newt and toe of frog/wool of bat and tongue of dog." People in the 16th century were more akin to DIY scientists than Macbeth’s three witches when it came to concocting home remedies for everything from hair loss and toothache, to kidney stones and fungal infections. Medical manuals targeted to the layperson were hugely popular at the time, according to Stefan Hanss, an early modern historian at the University of Manchester in the UK. "Reader-practitioners" would tinker with the various recipes, tweaking them as needed and making personalized notes in the margins. And they left telltale protein traces behind as they did so.
。业内人士推荐体育直播作为进阶阅读
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Сначала исследователи с помощью компьютерного моделирования определили возможные молекулярные «мишени» вещества. Анализ выявил более 180 потенциальных точек воздействия, связанных с воспалением, окислительным стрессом и фиброзом — процессом рубцевания ткани, который лежит в основе прогрессирования болезни. Затем результаты проверили на модели хронического поражения почек у крыс.
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